Apoquel Tablets for Dogs
Apoquel Tablets for Dogs
Apoquel Tablets for Dogs
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Apoquel Tablets for Dogs

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Apoquel® Tablets

Product Information

Apoquel® is used to provide dogs with fast, effective relief of allergic itch and inflammation due to atopic and allergic dermatitis.



Generic Name


Brand Names


Drug Class

Janus Kinase (JAK) Inhibitor, Antipuritic



Product Description & Form

Apoquel® 3.6 mg Tablets 1ct, 15 ct, 30 ct, 100 ct: 10 mm, white, oval tablet, scored in half, imprinted with AQ;S. (NDC 54771-8721-03, 54771-8721-02)

Apoquel® 5.4 mg Tablets 1ct, 30 ct, 100 ct: 11 mm, white, oval tablet, scored in half, imprinted with AQ;M. (NDC 54771-8722-03, 54771-8722-02)

Apoquel® 16 mg Tablets 1 ct, 15 ct, 30 ct, 100 ct: 16 mm, white, oval tablet, scored in half, imprinted with AQ;L. (NDC 54771-8723-03, 54771-8723-02)


  • Used for the control of itching associated with allergic dermatitis and control of atopic dermatitis in dogs
  • The inhibition of the Janus Kinase enzyme means the body is less likely to make substances that lead to inflammation and itching
  • Not a steroid, antihistamine, or an immunosuppressive agent
  • Fast and effective and begins to control allergic itch within 4 hours

Active Ingredients

Oclacitinib maleate


Apoquel® should be given orally as directed by your veterinarian. Apoquel® may be administered with or without food.

Missed Doses

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.

Side Effects

Side effects may include diarrhea, vomiting, anorexia, polydipsia, dermal lumps or lethargy. Notify your veterinarian if side effects appear and remain troublesome. 

Other side effects may occur, if you notice anything unusual, contact your veterinarian.

Drug & Food Interactions

The following drugs can potentially interact with oclacitinib: cyclosporine, glucocorticoids, and other immunosuppresive agents. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Make sure to tell your veterinarian what other medication or supplements you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.


Apoquel® is not for use in breeding dogs, or pregnant or lactating bitches.

Do not use on dogs less than 12 months of age or dogs with serious infections. Apoquel® may increase susceptibility to infection, including demodicosis, and exacerbate neoplastic conditions. Dogs receiving Apoquel® should be monitored for the development of infections, including demodicosis, and neoplasia. If dog shows signs of infection, difficulty breathing or is listless, or has a fever, contact your veterinarian immediately.  If you see abnormal skin changes or growths, contact your veterinarian. The use of Apoquel® has not been evaluated in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents.

Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.

Adverse Reactions

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Zoetis at 888-963-8471 or Vetsource customer service at 877-738-4443.


Store at 68°F to 77°F in controlled room temperature, excursions permitted between 59° to 104°F. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.

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